The mission of the CoHemis center is to promote human resources development, technology assessment, and joint applied research projects and programs with potential  benefits for more than one country in the Western Hemisphere aiming to serve the needs of the Americas with the participation of  engineering and science researchers faculty and graduate students from the different countries of the hemisphere. As its long range purpose, the center's mission is to become a decentralized hemispheric applied research organization in the context of the CoHemis Consortium. 

• Enhance the technological and human resources capabilities of Latin America and the Caribbean, and hence their social, economic and commercial development.
  
• Foster the protection of the hemisphere's environment and natural resources.
  
• Increase the global competitiveness and sustainability of Western Hemisphere industry.
  
• Bring high priority regional problems to the attention of researchers and sponsoring agencies across the different countries.
  
• Promote Puerto Rico and its University as ideal for facilitating and conducting effective technology transfer and educational efforts in key areas of sustainable development, where they have a comparative advantage.
  
• Increase opportunities available in Puerto Rico for quality graduate study in science and engineering, and thus the number and quality of Hispanic-American Engineering and applied science Ph.D.'s.
  
• Link key universities, science & technology institutions, and research centers throughout the Americas which are committed to hemispheric collaboration in research and education.
  
• Promote the creation of a multinational hemispheric advanced education and joint research network centered in the University of Puerto Rico, with the participation of the CoHemis Consortium. This network would provide research funds, student assistantships, and technology services to its member countries according to their priorities.